可加工生物活性云母/氟磷灰石玻璃陶瓷的制备及生物活性

来源期刊：中南大学学报(自然科学版)2006年第6期

论文作者：向其军 刘咏 黄伯云 盛小娴

文章页码：1025 - 1030

关键词：玻璃陶瓷;显微结构;生物活性;云母;氟磷灰石

Key words：glass-ceramics; microstructure; bioactivity; mica; fluorapatite

摘    要：采用高温熔铸法制备可加工生物活性云母/氟磷灰石玻璃陶瓷;用X射线衍射(XRD)、扫描电镜(SEM/EDS)和傅里叶变换红外(FTIR)光谱分析等手段对材料的相组成和微观形貌进行研究,测定材料的抗弯强度、硬度和断裂韧性等力学性能;采用体外模拟体液(SBF)浸泡法测试材料的生物活性。研究结果表明:氟磷灰石相呈针状,与人体骨和牙齿的磷灰石形貌相似,有利于提高材料的生物活性和生物相容性;氟磷灰石的形成是材料被迅速加热至高温进行热处理,使磷灰石以螺旋位错生长机制沿c轴晶化长大所致;经热处理获得的材料具有优良的力学性能,基本满足骨科和齿科用生物材料的性能要求;材料在体外模拟体液中浸泡3 d后,样品表面已有磷灰石层生成,表明该材料具有较高的生物活性。

Abstract: Machinable bioactive glass-ceramics containing mica and fluorapatite were prepared byhigh-temperature melting. The glass-ceramics were analyzed by means of X-ray diffractometry(XRD), scanning electron microscopy with energy dispersive spectrometer (SEM/EDS) and Fourier transform infrared reflection spectrometry(FTIR). The bending strength, hardness and fracture toughness of the materials were measured. To evaluate the bioactivity of the glass-ceramics,the specimens were soaked in the simulated body fluid (SBF). The results indicate that fluorapatite shows needle-like microstructure, which is similar to that in human bone and teeth. The formation of needle-like fluorapatite is related to the heat treatment procedure, which results in needle-like fluorapatite crystals by accelerating one-dimension growth along the c-axis through the screw dislocation growth mechanism. The mechanical properties of the glass-ceramics are close to those of the human bone and teeth. The bioactivity test results show that apatite layer is precipitated on the materials surface after 3 d immersion in SBF, which indicates the glass-ceramics have a good bioactivity.