药对川芎-羌活挥发油的气-质联用分析与化学计量学解析

来源期刊：中南大学学报(自然科学版)2007年第4期

论文作者：李晓如 赵君 兰正刚 梁逸曾

文章页码：681 - 681

关键词：川芎；羌活；挥发油；气相色谱-质谱；化学计量学解析法

Key words：Chuanxiong Rhizome; Notopterygium Root; essential oil; gas chromatography-mass spectrometry; chemometric resolution method

摘    要：采用气相色谱-质谱(GC/MS)法分离测定药对川芎-羌活、单味药川芎和羌活的挥发油成分，利用化学计量学解析法(CRM)对重叠的色谱峰进行解析，得到药对和各单味药的纯色谱曲线和质谱，通过质谱库对解析的纯组分进行定性，药对川芎-羌活、单味药川芎和羌活的定性分析结果分别为50，38和43个，占总含量的94.32%，83.19%和96.04%。实验结果表明，药对挥发油组分主要来自于单味药羌活，而化学组分种类基本上为2个单味药的加和，单味药挥发油组分的含量在药对中发生了变化。

Abstract: Analysis of volatile components in herbal pair (HP) Chuanxiong Rhizome-Notopterygium Root (CXR-NR), single herb CXR and NR was performed with two-dimensional gas chromatography-mass spectrometry (GC/MS) data coupled with chemometric resolution method (CRM). By means of these methods two-dimensional data, 38, 43 and 50 volatile chemical components in essential oil of CXR, NR, and HP CXR-NR were respectively determined qualitatively and quantitatively, accounting for 83.19%, 96.04%, and 94.32% total contents of essential oil of CXR, NR, and HP CXR-NR, respectively. The experimental results show that the number of volatile chemical components in CXR-NR, mainly from that of single herb NR, is almost equal to the sum of the number in the two single herbs, but the relative amounts, especially the ligustilide in CXR change.

基金信息：国家自然科学基金资助项目