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Preparation and functional characterization of tumor-targeted folic acid-chitosan conjugated nanoparticles loaded with mitoxantroneWANG Wei(王炜)1, TONG Chun-yi(童春义)2, LIU Xing-yan(刘星言)1, LI Tao(李涛)1... of Ophthalmology and Eye Research Center, The 2nd Xiangya Hospital,Central South University, Changsha 410011, China)Abstract:Folic acid conjugated chitosan was prepared by cross-linking reaction with 1-ethyl-3......
Self-assembled Nanoparticles based on Folic Acid Modifi ed Carboxymethyl Chitosan Conjugated with Targeting Antibody虎征宇1,ZHENG Hua1,LI Dan1,XIONG Xiong1,TAN Mingyuan1,HUANG Dan1,GUO Xing1,张雪琼1,严晗21... for acute myeloid leukemia(AML).Moreover,methotrexate(MTX)was chosen as modeldrug and encapsulate within folic acid modified carboxymethylchitosan(FACMCS)nanoparticles through self-assembling.The......
Folic Acid Functionalized Vertically Aligned Carbon Nanotube(FA-VACNT) Electrodes for Cancer Sensing ApplicationsSomayeh Zanganeh1,2,Fatemeh Khodadadei1,2,3,S.Ra?zadeh Tafti1,2,Mohammad Abdolahad1,21... was developed using amine-functionalized vertically aligned carbon nanotubes(VACNTs) conjugated to folic acid(FA) molecules. Speci?c binding of FA to folate receptor(FR) existing on the membrane......
Synthesis and characterization of NaYF4:Yb3+,Er3+@silica-N=folic acid nanocomplex for bioimaginable detecting MCF-7 breast cancer cellsHa Thi Phuong1,2,Tran Thu Huong1,3,Le Thi Vinh4,Hoang Thi...+,Er3+@silica-N=FA(folic acid) nanophosphors can be controlled with length of the rod about 300-800 nm and diameter of the rod about 100-200 nm.Phase structure of NaYF4:Yb3+,Er3+is in hexagonal crystal......
Synthesis and characterization of NaYF4:Yb3+,Er3+@silica-N=folic acid nanocomplex for bioimaginable detecting MCF-7 breast cancer cellsHa Thi Phuong1,2,Tran Thu Huong1,3,Le Thi Vinh4,Hoang Thi...+,Er3+@silica-N=FA(folic acid) nanophosphors can be controlled with length of the rod about 300-800 nm and diameter of the rod about 100-200 nm.Phase structure of NaYF4:Yb3+,Er3+is in hexagonal crystal......
; accepted 10 October 2012 Abstract: Highly biocompatible superparamagnetic Fe3O4 nanoparticles were synthesized by amide of folic acid (FA) ligands and the NH2-group onto the surface of Fe3O4... nanoparticles could be effectively mediated into the human hepatoma Bel 7402 cells through the binding of folate and folic acid receptor, enhancing the signal contrast of tumor tissue and surrounding normal......
末端带叶酸的星形聚己内酯的合成及表征 罗祥林1,李文龙1,吴瑶1,陈元维1 (1.四川大学,高分子科学与工程学院,四川,成都,610065;2.四川大学,高分子科学与工程国家重点实验室,四川,成都,610065) 摘要:用1,1,1-三羟甲基乙烷及2,2-二羟甲基丙酸为原料合成了树型分子R(CH_2OH)_6;然后以此树形分子引发ε-己内酯开环聚合,得到了六臂星形聚己内酯(Star PCL);再通过DCC使叶酸与星形聚己内酯各臂链端的羟基官反应,得到了链端接枝叶酸的星形聚己内酯(StarPCL-FA).~1H-NMR和FT-IR确证了产物的结构.结果表明,成功地制备了六臂星形聚己内酯-叶酸材料,它们有望成为一类新型的肿瘤靶向药物载体材料. 关键词:星形聚合物; 聚己内酯; 叶酸; 药物载体; star-shaped polymer; PCL; folic acid; drug......
Inhibition mechanism of aspartic acid on crystal growth of hydroxyapatite HUANG Su-ping(黄苏萍), ZHOU Ke-chao(周科朝), LI Zhi-you(李志友) State Key Laboratory of Powder Metallurgy, Central South...; Abstract: The effects of aspartic acid on the crystal growth, morphology of hydroxyapatite(HAP) crystal were investigated, and the inhibition......
Pressure acid leaching of zinc sulfide concentrate GU Yan(古 岩), ZHANG Ting-an(张廷安), LIU Yan(刘 燕), MU Wang-zhong(牟望重), ZHANG Wei-guang(张伟光),DOU Zhi-he(豆志河), JIANG Xiao-li(蒋孝丽) Key... temperature, solid-to-liquid ratio and additive amount on pressure acid leaching process of the zinc sulfide concentrate were studied. The results indicate that the additive can improve the reaction......
