具有生物降解功能的生物陶瓷材料研究

来源期刊：中南大学学报(自然科学版)1993年第4期

论文作者：阮建明 黄伯云 温金海 周江南

文章页码：509 - 514

关键词：生物活性陶瓷材料; 降解功能; 临床应用

Key words：bioactive ceramic material; biodegradating function; clinical application

摘    要：研究、制备了组元和结构类似于人体硬组织的多孔生物活性陶瓷材料HA-TCP[Ca₁₀PO₄₆OH₂-Ca₃PO₄₂]。在完成了生物实验和动物种植实验之后,该多孔生物活性材料在临床外科上得到了应用。X光显示表明,在短时间内植入的该材料能降解成硬组织、能在手术空洞中形成新骨小梁。文章较详细地介绍了HA-TCP粉末及材料的制备过程和适宜于软组织生长的孔隙结构和临床应用效果。

Abstract: A highly porous bioactive ceramic material HA-TCP [Ca₁₀PO₄₆OH₂-Ca₃PO₄₂] whose ingredients and phase structures are similar to those of the human hard tissue is studied and fabricated by powder metallurgytechnique. After biological examinations and animal implanting tests, the porous bioactive material is used inclinical surgery. The X-ray analysis shows that the implanting material can be degradated into hard tissue andnew bone bridge can be formed in operation vacancies in a short time. The preparing process of HA-TCP powders and porous HA-TCP materials, the pore structures which are suitable for soft tissue in growth and clinical results are described in considerable detail in this paper.