Physicochemical characterization of Baizhi particles by ultrafine pulverization

Lian-wei Yang1,2), Peng Sun1), Guo-sheng Gai1), Yu-fen Yang1), and Yu-rong Wang3) 1) Department of Material Science and Technology, Tsinghua University, Beijing 100084, China 2) Department of Material Science and Technology, Northeastern University at Qinhuangdao Branch, Qinhuangdao 066004, China 3) School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100029, China

摘 要：Baizhi, as a medicinal plant, has been demonstrated to be useful for the treatment of aches and pains in China. The physicochemical characterization of Baizhi particles is greatly influenced by ultrafine pulverization. To study the physicochemical characterization of Baizhi, the raw plant material of Baizhi was ground to 6 μm particles by a high speed centrifugal sheering (HSCS) pulverizer. The micron particles were characterized by optical microscopy and scanning electron microscopy (SEM). Imperatorin is one of the active ingredients of Baizhi, and its extraction yield is determined to evaluate the chemical characterization of Baizhi powder. Imperatorin was analyzed by high performance liquid chromatography (HPLC). The results show that after ultrafine pulverization, the plant cell walls are broken into pieces and the extraction yield of imperatorin is increased by 11.93% compared with the normal particles.

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